Gout (sometimes called gouty arthritis) is a common type of arthritis caused by too much uric acid in the bloodstream. The uric acid forms clumps of small, sharp crystals inside and around the joints, leading to sudden attacks of severe pain, swelling and redness.
Gout can be very painful but there are ways to treat the symptoms and reduce the risk that it will return.
What are the symptoms of gout?
An attack of gout can begin anytime, but it often starts at night. Any joint can be affected – the most common joints are the big toes, middle foot joints, ankles, knees, fingers and elbows. Sometimes it affects more than one joint at a time.
The affected joints can also be extremely tender to touch. Gout can affect any joints, but is most commonly seen at the base of the big toe. It can happen quickly – often people wake up in the middle of the night with severe pain and a feeling like the joint is on fire.
The symptoms of a gout attack include:
What causes gout?
Gout occurs when there are abnormally high levels of uric acid in the blood (called hyperuricaemia) and tissues. Uric acid is a waste product that forms when the body breaks down chemicals called purines. Purines are found in many foods and also occur naturally in the body. Normally, the body’s kidneys filter out excess uric acid and it’s excreted via the urine. But in people with gout, the uric acid accumulates in the body.
This can happen when the kidneys don’t get rid of enough uric acid or when there is an overproduction of uric acid by the body. This build up of uric acid may also cause kidney stones. While high uric acid levels in the blood lead to gout, it’s not clear why some people with high levels of uric acid develop gout but others with the same high levels don’t.
When uric acid builds up it can form small, jagged, needle-shaped crystals. It can take months or even years for the crystals to develop. They usually form in and around joints, and if they get into the small spaces between the joint they can cause severe pain, swelling and redness. This is known as a gout attack.
How long does an attack of gout last?
An attack of gout usually strikes unexpectedly, and often last between 3 and 10 days. Some people might have some ongoing pain or discomfort for several weeks.
Gout attacks often recur and without proper treatment, the attacks may become more frequent. If it’s not treated, gout tends to affect more joints over time.
A person should contact their doctor if they have symptoms of gout so that they can get it treated as soon as possible.
Someone who develops a fever plus severe, worsening joint pain should seek immediate medical attention. It could signal a serious infection inside the joint called septic arthritis.
Who gets gout?
In Australia, gout affects around 70,000 people each year. Gout can affect anyone, but it is much more common in men than women, in particular, middle-aged and older men. In women, gout usually occurs after menopause. Experts have found that the prevalence of gout in elderly male Australians is one of the highest in the world, second only to New Zealand.
Risk factors for developing gout
A person is more likely to develop gout if they have high levels of uric acid in their body, a condition known as hyperuricaemia.
Things that can increase levels of uric acid include:
Tests for gout
A doctor can often diagnose gout based on the symptoms and a person’s medical history. They will also ask the person about their diet and alcohol intake.
Sometimes the doctor will do blood tests to measure the amount of uric acid in the blood, although this may not be conclusive of gout.
The doctor may want to take a sample of fluid from the joint to check for the presence of uric acid crystals or to check for signs of infection.
X-rays are not usually done but sometimes an ultrasound is done to see if there are crystals in the joints.
Complications of gout
Gout can result in some complications, especially if left untreated.
How is gout treated?
The treatment of gout involves several stages:
Treatment of a gout attack
Australian guidelines recommend treatment with non-steroidal anti-inflammatory medication (NSAIDs) for an attack of gout. These work to reduce inflammation and pain. Examples include indomethacin (e.g. Arthrexin), naproxen sodium (e.g. Crysanal) and etoricoxib (Arcoxia).
If NSAIDs can’t be tolerated or the person has a history of ulcers then they may try:
Resting the joint and applying ice packs may also help with pain and inflammation. When the affected joint is a big toe, a box or cage to keep the bedclothes off the toe may be helpful.
Treatment to prevent further attacks
People can reduce their chances of having another attack of gout by taking certain medication and making lifestyle changes to reduce the level of uric acid in the body:
People experiencing gout attacks should avoid medicines containing aspirin as these can make gout worse.
Lifestyle changes to prevent gout attacks
Preventing acute gout attacks is just as important as treating the attacks of gout. Prevention of gout generally involves: